Jay Fitzgerald Dorsey, M.D., Ph.D.

(215) 662-2428

Smilow Center for Translational Research
8-135 Bldg 421
3400 Civic Center Blvd
Philadelphia, PA 19104


Associate Professor of Radiation Oncology

Attending Radiation Oncologist, Hospital of the University of Pennsylvania

Co-Leader, Radiation Oncology Translational Center of Excellence, Abramson Cancer Center

Director, SUPERS@Penn

As an Attending Radiation Oncologist and Associate Professor at Penn Medicine and the University of Pennsylvania, I have over 15 years of experience in treating primary and metastatic tumors of the central nervous system, using state-of-the-art techniques such as proton therapy and stereotactic radiosurgery. I have ABR board-certification in Radiation Oncology, a PhD in Molecular Oncology from Moffitt/USF and residency training in Therapeutic Radiology at Penn. I am a designated Gamma Knife Authorized User (AU) and serve as Chair of the DSMB at the Nuclear Imaging Institute.

I am also a physician-scientist, translational researcher and educator in the field of cancer and radiation biology, genomics, biomarkers, and cancer nanotechnology. I have been continuously funded by the NIH for the past decade and have published in the AACR, Cell, Science, and Nature journals. I participate (as a member or panel chair) in NCI CSR study sections for scientific review of grant applications submitted to the NIH. Currently, I serve on the Radiation Therapeutics and Biology (RTB) NIH study section. I lead an R01-funded translational lab that explores novel strategies to overcome resistance and enhance sensitivity to therapies in brain tumors and other solid cancers. I am Co-Leader of the Radiation Oncology Translational Center of Excellence at Penn, member of the Institutional Review Board (IRB) at the Abramson Cancer Center, and the Director of the NIH-sponsored SUPERS@PENN program, which aims to pipeline the next generation of scientists into careers in radiation-related sciences. My mission is to advance the understanding and treatment of cancer through innovation, collaboration, and mentorship.